Best pain relievers Deals Online in the US
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Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)Free ShippingAmazon Basic Care 
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count (Packaging may vary)Free ShippingAmazon Basic Care
Voltaren 3 Pack Arthritis Pain Reliever & Anti-Inflammation Topical Gel 1.76 oz- Best Value
30% OffTylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC MedicineFree ShippingTylenol 
Advil Ibuprofen Pain Reliever/Fever Reducer 200 mg Coated Tablets 200 ea - 3PK
17% OffTylenol Extra Strength Pain Relief Pills, Acetaminophen 500mg Caplets, Pain Reliever and Fever Reducer Medicine for Headache, Backache, Toothache & Minor Arthritis, 100 Count BottleFree ShippingTylenol
Advil Pain Reliever and Fever Reducer, Pain Relief Medicine with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 100 Coated TabletsFree ShippingAdvil-
PARACETAMOL TABLETS 500mg Pain Reliever,Quick Relief for Headache Fever, 150,Tab
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20% OffMotrin Dual Action with Tylenol, Ibuprofen & Acetaminophen Fast-Acting Dual Action Pain Reliever for Minor Aches & Pains, Ibuprofen (NSAID) 125 mg & Acetaminophen 250 mg, 120 ctFree ShippingMotrin
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AleveX Pain Relieving Lotion | Max Strength Menthol | Long Lasting Cooling 1/26+
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Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 100 Count (Packaging may vary)Free ShippingAmazon Basic Care
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Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets, Pain Reliever & Fever Reducer, Medicine for Body , 250 CountFree ShippingAleve
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Aleve Back & Muscle Pain Reliever Naproxen Sodium Tablets, 200 Count Exp: 08/25
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Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen for Minor Arthritis & Joint Pain, Fever Reducer, Extended Release, Gentle on Stomach, 100 ctFree ShippingTylenol
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China Gel topical pain reliever 8 ounces, green *Made in the USA*
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Amazon Basic Care Naproxen Sodium Tablets 220 mg, Pain Reliever/Fever Reducer (NSAID), Muscular Aches, Backache, Headache, Toothache, Minor Arthritis Pain Relief & More, 300 Count (Packaging may vary)Free ShippingAmazon Basic Care
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Voltaren Arthritis Pain Reliever GEL 3.53oz tube Topical treatment NIB 10/2025
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11% OffAdvil Dual Action Coated Caplets with Acetaminophen, 250 Mg Ibuprofen and 500 Mg Acetaminophen Per Dose (2 Dose Equivalent) for 8 Hour Pain Relief- 216 CountFree ShippingAdvil
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Bayer Aspirin Pain Reliever Low Dose 81mg 300 Coated Tablets EXP: 12/2026 Sealed
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GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 CountFree ShippingGoodSense
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Salonpas 140 Pain Relieving Patches External Arthritis Back Relief EXP 11/2026
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Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 CountFree ShippingAmazon Basic Care
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1000 CAPLETS Compare to Tylenol Extra Strength 500mg Exp9/26 Pain Reliever Fever
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11% OffAdvil Pain Reliever and Fever Reducer, Pain Relief Medicine with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 200 Coated TabletsFree ShippingAdvil
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New Advil Migraine Pain and Headache Reliever Ibuprofen, 200 mg Liquid 80 Count
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Advil Dual Action Back Pain Caplets Delivers 125mg Ibuprofen and 250mg Acetaminophen Per Dose for 8 Hours of Back Pain Relief - 144 CountFree ShippingAdvil
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SALONPAS 140 Pain Relieving Patches external Arthritis Back Relief NEW!Free Shipping
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A+Health Ibuprofen 200 Mg Softgels, Pain Reliever/Fever Reducer (NSAID), 300 CountFree ShippingA+Health
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Voltaren 3 Pack Arthritis Pain Reliever & Anti-Inflammation Topical Gel 1.76 oz
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Amazon Basic Care Back and Muscle Pain, 220 mg, 12-Hour Pain Relief, Naproxen Sodium Tablets, Pain Reliever and Fever Reducer, 90 CountFree ShippingAmazon Basic Care
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Bactine Max Pain Relieving Cleansing Spray 5 Ounces Pack of 2
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Advil Pain Reliever and Fever Reducer, Pain Relief Medicine with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 10 Coated TabletsFree ShippingAdvil
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Sombra Warm Therapy Pain Reliever 1 Gallon With Pump 095
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16% OffMotrin IB Ibuprofen 200mg Tablets, Ibuprofen Pain & Fever Reliever for Headache, Backache, Muscular Aches, Menstrual Pain & Minor Arthritis Pain, Over-The-Counter NSAID Medicine, 225 ctFree ShippingMotrin
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Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2Free ShippingVoltaren
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41% OffAleve Pain Relief Naproxen Sodium Caplets ‐ 50 CountFree ShippingAleve
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Advil Pain Reliever and Fever Reducer, Ibuprofen 200mg for Pain Relief - 300 Count, Advil PM Pain Reliever and Nighttime Sleep Aid, Ibuprofen for Pain Relief and Diphenhydramine Citrate - 2 CountFree ShippingAdvil
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Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg, Extra Strength Pain Reliever and Fever Reducer, 400 CountFree ShippingAmazon Basic Care
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Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen, 25 mg Diphenhydramine HCl, Fast-Acting, Non-Habit Forming, Pain Relief Medicine for Aches & Cramps, 100 CtFree ShippingTylenol
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17% OffGenCare - Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets) Value Pack | Head Pain, Muscle Aches, Back Pain & Body | Generic ExcedrEn Extra StrengthFree ShippingGenCare
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A+Health Dual Action Acetaminophen 250 mg and Ibuprofen (NSAID) 125mg Pain Reliever Caplets, 216 CountFree ShippingA+Health
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Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Headache, Muscular Aches, Arthritis, Backache and More, 100 Count (Pack of 1)Free ShippingAmazon Basic Care
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22% OffAmazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Arthritis, Toothache, Backache and More, 100 CountFree ShippingAmazon Basic Care
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28% OffTylenol Extra Strength Dissolve Powder Packs, 500 mg Acetaminophen Pain Reliever & Fever Reducer Medicine, Fast Relief for Minor Aches & Pains, Ibuprofen- & Aspirin-Free, On-the-Go Berry Flavor, 32 CtFree ShippingTylenol
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15% OffBoiron Arnicare Tablets for Pain Relief from Muscle Pain, Joint Soreness, Swelling from Injury or Bruises - 60 CountFree ShippingBoiron
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Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g TubeFree ShippingVoltaren
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16% OffAmazon Basic Care Dual Action Acetaminophen 250 mg and Ibuprofen (NSAID) 125 mg Tablets, 216 CountFree ShippingAmazon Basic Care
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Advil Liqui-Gels Minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 80 Liquid Filled CapsulesFree ShippingAdvil
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Amazon Basic Care Ibuprofen Liquid Gels 200 mg, Pain Reliever/Fever Reducer Liquid Filled Capsules, For Headache, Toothache, Backache, Menstrual Cramps and More, 160 CountFree ShippingAmazon Basic Care
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Bayer Extra Strength 500mg Aspirin Plus Caffeine for Powerful Pain Relief, 200 Coated CapletsFree ShippingBayer
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TIME-CAP LABS, INC. Timely Ibuprofen 200mg 500 Tablets - (NSAID) Pain Relief Pills for Headache, Menstrual Pain, Tooth Aches, Muscle Pain, Arthritis Pain, Body AchesFree ShippingTIME-CAP LABS, INC.
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Vicks PainQuil & PainQuil PM Pain Relief Liquid, 1000mg Acetaminophen, 2x12 ozFree ShippingVicks
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Compare to Tylenol Arthritis Pain Active Ingredient. - Member's Mark - Arthritis Pain Reliever, Extended Release, Acetaminophen 650 mg, 400 CapletsQFree ShippingMEMBER´S MARK
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11% OffAmazon Basic Care Naproxen Sodium 220 Mg Liquid Gels, Pain Reliever/Fever Reducer (NSAID), 180 Count (previously A+ health)Free ShippingAmazon Basic Care
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Salonpas Pain Relieving Patch for Back, Neck, Shoulder, Knee Pain and Muscle Soreness - 8 Hour Pain Relief - 60 CountFree ShippingSalonpas
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A+Health Mini Ibuprofen 200 Mg Softgels, Pain Reliever/Fever Reducer (NSAID), 500 CountFree ShippingA+Health
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HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))Free ShippingHealthA2Z
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40% OffAmazon Basic Care Headache Pain Relief Naproxen Sodium Tablets 220 mg, Also Relieves Arthritis, Muscular Aches, Backache, Menstrual Cramps and Toothache, 90 CountFree ShippingAmazon Basic Care
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Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g Tube And 20 g Travel Size TubeFree ShippingVoltaren
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Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 CountFree ShippingExcedrin
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24% OffTylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer, 100 CountFree ShippingTylenol
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Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Medication for Arthritis Pain, 160 CountFree ShippingAleve
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Timely Acetaminophen 500mg - 500 Caplets - Extra Strength Pain Relief - Compared to the active ingredient in Extra Strength - Menstrual Cramps, Fever Reducer, Minor Pain of ArthritisFree ShippingTIME-CAP LABS, INC.
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13% OffGenCare - Tension Headache Relief Pain Reliever with Acetaminophen 500 mg & Caffeine 65 mg (200 Caplets) Best Value Bulk Extra Strength for Head, Migraine, Joint Pain & Body Ache Relief MedicineFree ShippingGenCare
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26% OffTylenol 8 Hour Muscle Aches & Pain Relief Extended-Release Tablets with 650 mg Acetaminophen, Fever Reducer & Pain Medicine for Muscles, Joints, Body, and Backache Pain Relief, 24 CountFree ShippingTylenol
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Amazon Basic Care Ibuprofen PM, Ibuprofen 200 mg and Diphenhydramine Citrate 38 mg Tablets, Pain Reliever and Nighttime Sleep-Aid, 120 Count (Packaging may vary)Free ShippingAmazon Basic Care
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HealthA2Z® Dual Action Pain Relief | Acetaminophen 250mg & Ibuprofen (NSAID) 125mg | Contains Two Medicines | Relief from Headache, Fever & Backache (150 Caplets)Free ShippingHealthA2Z
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Advil Liqui-Gels Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 200 Capsules, Advil PM Ibuprofen - 2 CtFree ShippingAdvil
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Amazon Basic Care Acetaminophen PM Caplets, Pain Reliever Plus Nighttime Sleep Aid, Extra Strength, Helps Occasional Minor Aches, Pains and Headache Relief, 100 Count, Packaging may varyFree ShippingAmazon Basic Care
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17% OffVoltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 gFree ShippingVoltaren
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Biofreeze Roll On Pain Relief for Knee, Neck, Hip, Joint, Shoulder, & Simple Backache, Arthritis Pain Reliever, Sore Muscle Relief, Roll On Menthol Gel 3 Fl Oz (Pack of 3)Free ShippingBiofreeze
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Excedrin Extra Strength Pain Relief Caplets for Headache Relief, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever, 200 CountExcedrin
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HealthA2Z® Pain Relief Extended Release | Acetaminophen 650mg | 250 Caplets | 8 Hours | Arthiritis Pain | Pain Reliever - Fever Reducer | Contains no Aspirin (250 Count)Free ShippingHealthA2Z
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Percogesic Backache Relief Pain Reliever, Maximum Strength, 48 TabletsFree ShippingPercogesic
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29% OffHealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)Free ShippingHealthCareAisle
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Penetrex Joint & Muscle Therapy Roll On - Soothing Gel for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - 3ozFree ShippingPenetrex
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Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 2.3 ozFree ShippingAdvil
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ABSORBINE JR. Pro Maximum-Strength Lidocaine Roll-On for Fast Nerve & Muscle Pain Relief - Non-Greasy, Long-Lasting Formula for Arthritis, Aches, Strains, & More - 2.5 oz - Pack of 1Free ShippingABSORBINE JR.
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TIME-CAP LABS, INC. Timely Ibuprofen 200mg 200 Tablets - (NSAID) Pain Relief Pills for Headache, Menstrual Pain, Tooth Aches, Muscle Pain, Arthritis Pain, Body AchesFree ShippingTIME-CAP LABS, INC.
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TIME-CAP LABS, INC. Timely Acetaminophen 650 MG - 400 Caplets - Extended Release - Joint Pain Relief, Pain Reliever & Arthritis Pain ReliefFree ShippingTIME-CAP LABS, INC.
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Tylenol Precise Cooling Numbing Cream, Maximum Strength 4% Lidocaine & 1% Menthol Topical Analgesic, Pain Relief Cream for Back, Muscle & Joint, Rollerball Applicator, Fast-Acting, Light Scent, 4 ozFree ShippingTylenol
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37% OffAspercreme Odor Free Max Strength Lidocaine Pain Relief Liquid with Roll-On No Mess Applicator, 2.5 oz.Free ShippingAspercreme
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18% OffAdvil Targeted Relief Pain Relieving Cream with Massage Applicator, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain, 2.5 ozFree ShippingAdvil
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Advil Dual Action Coated Caplets with Acetaminophen, 125mg Ibuprofen and 250mg Acetaminophen Per Caplet for 8 Hour Pain Relief - 18 CountFree ShippingAdvil
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17% OffHealthCareAisle Naproxen Sodium, 220 mg - 200 caplets - Pain Reliever and Fever Reducer, Up to 12 Hours of ReliefFree ShippingHealthCareAisle
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20% OffAdvil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 8 Liquid Filled CapsulesFree ShippingAdvil
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Amazon Basic Care Maximum Strength OTC Pain Relief , 4% Lidocaine Patch, 3.9” x 5.5”, 15-Count Box (Previously HealthWise)Free ShippingAmazon Basic Care
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Amazon Basic Care Migraine Relief, Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, Headache Pain Reliever/Pain Reliever Aid, 200 CountFree ShippingAmazon Basic Care
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Nervive Pain Relieving Roll On Liquid, Max Strength No-Mess Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 2.5ozFree ShippingNervive
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HealthA2Z® Ibuprofen 200mg | Pain Relief | Body Aches | Headache | Arthritis | Cramps | Back Pain | Fever Reducer (100 Count)Free ShippingHealthA2Z
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Bayer Aspirin Low Dose 81 mg Chewable Tablets, Pain Reliever, Orange Flavored, 216 Tablets (6 Pack)Free ShippingBayer
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HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))Free ShippingHealthA2Z
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Bayer Genuine Aspirin 325 mg, Pain Reliever and Fever Reducer, Head, Muscle, Minor Arthritis, Back, Tooth, and Menstrual Pain, 300 Coated TabletsFree ShippingBayer
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Genexa Clean Acetaminophen 500mg Extra Strength, Dye Free Pain Reliever Fever Reducer, 0% Artificial Additives, Pain Medicine for Adults, Relieves Headache, Backache, Minor Arthritis Pain, 100 TabletsFree ShippingGenexa
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14% OffGoodSense Ibuprofen Tablets - 200 mg - Fever Reducer & Pain Relief for Body Aches, Headache, Arthritis Pain, Menstrual Cramps, 500 CountFree ShippingGoodSense
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27% OffAmazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, 100 Count (Packaging may vary)Free ShippingAmazon Basic Care
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Aleve Liquid Capsules, Naproxen Sodium Capsules 220 mg (NSAID), Pain Reliever/Fever Reducer, Fast Pain Relief, 120 CountFree ShippingALEVE
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29% OffExcedrin Migraine Relief Caplets for Migraine Symptoms, Acetaminophen 250mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever, 24 CountFree ShippingExcedrin
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Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0ozFree ShippingNervive
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14% OffBiofreeze Professional Pain Relief Spray for Knee, Neck, Hip, Joint, Shoulder, & Simple Backache, Arthritis Pain Reliever, Sore Muscle Relief, Colorless Menthol Spray 4 Fl Oz (Pack of 3)Free ShippingBiofreeze
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Frankincense and Myrrh Arthritis Pain Reliever Therapy Lotion – Topical Arthritis Pain Relief Cream and Hydrating Skin Repair, Body Relief for Sciatica, Knee, Back, Joints, Neck, Hands, 3 Oz - 1 PackFree ShippingFRANKINCENSE & MYRRH
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15% OffBC Powder Original Strength Pain Reliever, Aspirin Dissolve Packs, 50 CountFree ShippingBC
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Tylenol Extra Strength 500 mg Acetaminophen Caplets, Pain Reliever & Fever Reducer, Acetaminophen for Minor Arthritis Pain, Headache, Backache & Menstrual Pain Relief, Travel Size, 6 CtFree ShippingTylenol
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HealthA2Z® Naproxen Sodium | 220mg | 300 Counts | NSAID | Fast Pain Relief | Fever ReducerFree ShippingHealthA2Z
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Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 OuncesFree ShippingIcy Hot
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28% OffSalonpas Pain Relieving Patch, LARGE, 6 Count, for Back, Neck, Shoulder, Knee Pain and Muscle Soreness, 8 Hour Pain ReliefFree ShippingSalonpas
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Bayer Rapid Relief Powder Packs with Aspirin & Caffeine, Dissolvable Fast Acting Pain Relief for Headache, Muscle and Body Pain, Raspberry Flavor (Packaging may vary), Pack of 3 x 10 CountFree ShippingBayer
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Aleve Pain Reliever & Fever Reducer Tablets, Naproxen Sodium, Headache, Back and Body Pain Relief Medicine, 270 CountFree ShippingAleve
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Biofreeze Roll On Pain Relief, Knee & Lower Back Relief, Arthritis Pain Reliever, Sore Muscle Relief, Neck Pain Relief, Cooling Joint Pain, FSA Eligible, Menthol Gel 2.5 Fl OzFree ShippingBiofreeze
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Puregen Labs Adult Extra Strength Acetaminophen Liquid 500mg/15ml - 8 fl oz Rapid Burst Pain Reliever/Fever Reducer, Cherry Flavor | Muscle & Joint Pain Relief | Arthritis Pain ReliefFree ShippingP Puregen Labs
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33% OffBoiron Arnicare Gel Natural Soothing Relief for Joint Pain, Muscle Pain, Inflammation, Soreness, and Bruises - Non-greasy and Fragrance-Free - 2.6 ozFree ShippingBoiron
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Goody's Pain Relief Powders, Extra Strength Headache Powder Mixed Fruit Blast, 24 ct (Pack of 1)Free ShippingGoody's
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34% OffBC Pain Relief Powder, Arthritis Pain, 50 ct (Pack of 1)Free ShippingBC
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23% OffNeosporin + Lidocaine First Aid Antibiotic Ointment, Maximum Strength & Fast-Acting Topical Pain Reliever, 24-Hour Infection Protection That Numbs Away The Pain, Bacitracin Zinc, 0.5 ozFree ShippingNeosporin
114 Pain Relievers deals are available from:
Amazon, eBay stores, starting from $2.00.
The biggest discount we found is 41% on Aleve Pain Relief Naproxen Sodium Caplets ‐ 50 Count at Amazon.
The lowest price we found is $2.00 while the highest is $178.20.
Prices for the best Pain Relievers deals average at $15.70.
Last updated on September 6, 2025.
We scanned these quality online stores and more to deliver you with the best offers online available for Pain Relievers.