Best sinus medicine Deals Online in the US
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20% OffSudafed PE Sinus Pressure Relief Plus Pain Relief Tablets, Maximum Strength, Non-Drowsy Decongestant, OTC Sinus Medicine with Acetaminophen and Phenylephrine HCl Nasal Decongestant, 24 CTSudafed - Best Value
28% OffTylenol Sinus Severe Daytime Caplets, Non-Drowsy, Pain Reliever, Pressure and Nasal Congestion Relief, Fever Reducer, Expectorant, Acetaminophen, Guaifenesin, Phenylephrine HCL, 24 CountTylenol 
Hyland's Kids Cold and Cough, Daytime Grape Cough Syrup Medicine for Kids Ages 4
16% OffTylenol Sinus + Headache Daytime Non-Drowsy Relief Caplets, Acetaminophen 325mg, Phenylephrine HCI 5mg, Nasal Decongestant for Sinus Pain, Headache & Nasal Congestion Relief, Fever Reduction, 24 CountTylenol
9-Pack Daytime Severe Cold & Flu Relief – Non-Drowsy Cold /Flu Medicine
Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 20 Coated TabletsAdvil
GenCare Nasal Decongestant PE – Phenylephrine HCl 10mg Tablets (Bulk 300 Count) Non-Drowsy Sinus Pressure Relief & Nasal Congestion Relief, Stuffy Nose Decongestants for Adults – Compare to Sudafed PEGenCare-
Mucinex Sinus-Max Max Pressure Pain & Cough, 24 Capsules🎈09/2026🎈
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Vicks Sinex SEVERE LiquiCaps, All-In-One Sinus Relief, Non-Drowsy, Nasal Decongestant, Maximum Strength Relief of Sinus Headache, Pain, Pressure, & Congestion, 24 LiquiCapsVicks
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(2)Mucinex Children's Cough Medicine Cherry Flavor Ages 4+ Exp 10/26
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14% OffBoiron SinusCalm Tablets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 60 CountBoiron
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Sinus Infection Treatment & Symptoms | Request prescription for sinus medication like nasal spray, antibiotics for sinus headache & pain symptom relief from an online doctor, NP, or PAAmazon One Medical
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Hyland's Kids Cold and Cough, Nighttime Grape Cough Syrup Medicine for Kids Ages
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14% OffSudafed PE Sinus Congestion Relief Tablets, Maximum Strength, Non-Drowsy, 10 mg Phenylephrine HCI Nasal Decongestant for Sinus Pressure and Congestion Due to Cold or Allergies, 36 ctSudafed
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Hyland's Kids Nighttime Organic Cough Syrup and Immune Support with Agave,
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FLUTICASONE 50 MCG (120 SPRAYS) NASAL SPRAYAmazon Pharmacy
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Children's Dimetapp Cold & Cough, 8 oz | CVS
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Mucinex Rapid Clear Maximum Strength Cold Medicine & Expectorant, Fever, Pain, Headache, & Excess Mucus Relief with Acetaminophen & Guaifenesin, Rapid Release Caplets for Adults, 20 CountMucinex
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Hyland's Kids Cold and Cough, Day and Night Combo Pack Grape, Cold Medicine for
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28% OffSudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant & Antihistamine Tablets with Phenylephrine HCl & Diphenhydramine HCl, Helps Nasal & Sinus Pressure & Congestion, 20 ctSudafed
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Hyland's Kids Daytime Organic Cough Syrup and Immune Support with Agave,
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SUDOGEST 30 MG TABMAJOR PHARMA
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Wellements Organic Baby Cough Syrup Day & Night Value Combo Pack | Daytime &
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Vicks Sinex SEVERE, All-In-One Sinus + Mucus Relief, Non-Drowsy, Loosens Mucus, Maximum Strength Relief of Pain, Pressure, Congestion, & Headache Relief, 24 LiquiCapsVicks
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HealthA2Z Allergy Medicine Loratadine, 24 Hour Non-Drowsy Allergy Pill and Sinus
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AXIV Sinus Severe + Mucus Relief, Non-Drowsy, Loosens Mucus, Maximum Strength Relief of Pain, Pressure, Congestion, & Headache Ease, 24 Softgels.AXIV
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Advil Sinus Congestion and Pain, Relief Medicine, Pain Reliever and...
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50% OffHealthA2Z® Decongestant PE | Phenylephrine HCl 10 mg | Nasal & Sinus Congestion Relief Due to Cold & Allergies (300 Count (Pack of 1))HealthA2Z
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Sinusitis Drops Homeopathic Medicine For Relieving Sinus Congestion & Irritation
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Sudafed PE Head Congestion Plus Mucus Relief Tablets for Sinus Pressure, Congestion and Headache, Non-Drowsy Decongestant with Acetaminophen, Guaifenesin, Phenylephrine HCI, 24 ctSudafed
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Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion
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Mucinex Maximum Strength Sinus-Max Severe Congestion & Pain + Nightshift Sinus Liquid, Cold and Flu Medicine for Adults, Over-the-Counter Medication for Multi-Symptom Relief, 2x6 Fl OzMucinex
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4 PACK HALLS Relief Mentho-Lyptus Cough Drops, Economy Pack, 80 Count
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14% OffVicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)Vicks
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ValuMeds Nasal Decongestant PE Phenylephrine HCl 10mg Tablets (Bulk 300 Count) Non-Drowsy Sinus Pressure Relief & Nasal Congestion Relief, Stuffy Nose Decongestants for Adults | Compare to Sudafed PEValuMeds
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AXIV Sinus Head Congestion Relief, Non-Drowsy, Maximum Strength for Sinus Pressure, Headache, Pain & Stuffy Nose, 24 SoftgelsAXIV
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10% OffAlka-Seltzer Plus Maximum Strength PowerMax Sinus Congestion & Pain Medicine, Day + Night Liquid Gels - Powerful Relief for Cold and Flu, + Sinus Congestion for Adults and Children 12+ Years, 24 CountALKA-SELTZER PLUS
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Alka-Seltzer Plus Maximum Strength Power Max Sinus, Allergy and Cough Medicine for Adults and Children 12 Years and Older - Relieves Symptoms from Allergies, Colds or Hay Fever, 24 CountALKA-SELTZER PLUS
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34% OffAdvil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 50 Coated TabletsAdvil
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Mucinex Nightshift Sinus, Cold And Flu Cough Medicine For Adults, Powerful Nighttime Sinus Medicine For Sinus Relief, Sore Throat Relief, Cough Suppressant & Nasal Decongestant For Adults, 6 Fl OzMucinex
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23% OffMucinex Severe Congestion & Pain Relief, Sinus-Max Max Strength, 6oz Clears Sinus & Nasal Congestion, Relieves Headache & Fever, Thins & Loosens MucusMucinex
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Boiron SinusCalm Allergy Tablets for Relief from Sinus Pressure, Sinus Headache, or Sinus Congestion and Pain - 60 CountBoiron
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11% OffNUVICARE Max Strength PE Phenylephrine HCl 10mg Non Drowsy Nasal Decongestant - Allergy Sinus Congestion Relief Compare to Sudafed PE Decongestant Tablets - Sinus Decongestants for Adults (100 Count)NUVICARE
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Mucinex Sinus-Max Nasal Spray Decongestant, 12 Hour Over-The-Counter Medication Nose Spray for Sinus Relief, Nasal Decongestants for Adults & Sinus Congestion, Clear & Cool 3/4 Fl Oz(22ML)Mucinex
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15% OffAdvil Allergy and Congestion Relief Tablets, Pain Reliever, Fever Reducer and Allergy Relief with Ibuprofen, Phenylephrine HCl and Chlorpheniramine Maleate 4 mg - 20 Coated TabletsAdvil
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Tylenol Sinus Severe Daytime Caplets with Acetaminophen 325mg, Guaifenesin 200mg & Phenylephrine HCl 5mg, Non-Drowsy Pain Reliever, Expectorant & Nasal Decongestant, 50 Travel Packs of 2 ctTylenol
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27% OffMedi-First 80913 Sinus Decongestant, Nasal Decongestion Pills, 500 CountMedique
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Alka-Seltzer Plus Maximum Strength PowerMax Sinus Congestion and Pain Liquid Gels - Nasal Decongestant, Cough Suppressant, and Pain Relief for Adults and Children 12 Years and Older, 24 CountALKA-SELTZER PLUS
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10% OffGaia Herbs Sinus & Lung Supreme - Lung Support Supplement with Herbs Traditionally Used to Support Respiratory & Sinus Health* - Vegan, Gluten-Free & Dairy Free - 60 Liquid Phyto-Caps (60 Servings)Gaia Herbs
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15% OffHealthA2Z® Decongestant PE | Phenylephrine HCl 10 mg | Maximum Strength | Nasal & Sinus Congestion Relief Due to Cold & Allergies (90 Count (Pack of 1))HealthA2Z
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24% OffBoiron SinusCalm Pellets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 2 Count (160 Pellets)Boiron
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Puregen Labs Nasal Decongestant PE 100 Tablets | Phenylephrine HCl 10 mg Tablets | Maximum Strength | Non Drowsy Nasal & Sinus Congestion Relief Due to Cold or Allergies (1)P Puregen Labs
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Medique Medi-First 2546 Sinus Decongestant, 100-Packets of 1Medique
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Christopher's Original Formulas Sinus Plus, Sinus Support Capsules, Whole Herb Synergistic Blend, 100 CountChristopher's Original Formulas
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RidgeCrest Herbals SinusClear, Complete Formula for Sinus and Nasal Health with Mullein Leaf, Bromelain, Vitamin C, and Zinc, for Healthy Mucus, Immune & Respiratory Support, (60 Veg Caps, 30 Serv)RidgeCrest Herbals
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13% OffNeilMed Sinus Rinse All Natural Relief Premixed Refill Packets 100 Count (Pack of 1)NeilMed
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MediNatura BHI Sinus Congestion Relief – Plant & Mineral-Based Tablets for Sinus Pressure, Headaches & Nasal Congestion – Non-Drowsy, Non-Addictive & Fast-Working-Chewable – 100 CountMediNatura
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PhysiciansCare Sinus Decongestant Congestion Medication, 2 Tablets Per Packet, Box Of 50PhysiciansCare
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Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid OunceMucinex
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Afrin No Drip Severe Congestion Pump Mist Nasal Spray 12 Hour Relief 20 mL Bottle (Pack of 2)Afrin
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Vicks Dayquil & Nyquil Severe Co-Pack, Cold & Flu Medicine, Powerful Relief For Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, And Cough, 48 LiquicapsVicks
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Mucinex Fast-Max & NightShift Combo Pack - Max Strength Cough & Cold Medicines For Mucus Relief, Chest Congestion, Nasal Congestion, Sinus Congestion, Sinus Pressure, Cough Symptom Relief (2x 6 FL OZ)Mucinex
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28% OffAdvil Allergy and Congestion Relief Tablets, Pain Reliever, Fever Reducer and Allergy Relief with Ibuprofen, Phenylephrine HCl and Chlorpheniramine Maleate 4 mg - 50 Coated TabletsAdvil
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Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2Vicks
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Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels for Multi-Symptom Relief, Sore Throat, Cough, Nasal Congestion, Headache, 48 Count (Pack of 1)Amazon Basic Care
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Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 SpraysVicks
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Beekeeper's Naturals All Natural Sinus Support for Adults, Seasonal Nasal Care Relief with Propolis, Quercetin, Bromelain, Nettle Leaf, & Vegan Capsule, Blocks or Suppresses Histamine, 60 ctBeekeeper's Naturals
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Vicks DayQuil Severe Cold & Flu Liquid Medicine, Daytime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Chest Congestion, Stuffy Nose, Nasal Congestion, Sinus Pressure, & Cough, 2x12ozVicks
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WELMATE Nasal Decongestant PE Phenylephrine HCl 10 mg (200 Count) Maximum Strength, Non-Drowsy Sinus Congestion & Pressure Relief, Sinus Decongestant Tablets for AdultsWELMATE
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23% OffNeilMed Sinus Rinse - A Complete Sinus Nasal Rinse Kit, 50 count (Pack of 1) Count may varyNeilMed
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Beekeepers Naturals Propolis Sinus Support, 60 CTBeekeeper's Naturals
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Mucinex Maximum Strength Sinus-Max (Day) Pressure, Pain & Cough & Nightshift (Night) Sinus Caplets, Fast Release, Powerful Multi-Symptom Relief, 20 caplets (12 Day time + 8 Night time)Mucinex
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Boiron SinusCalm Tabs - 100 Count for Sinus Pressure and Pain Relief, Runny Nose, Congestion, Headache - Sinus Calm Meltaway TabletsBoiron
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23% OffBenadryl Allergy Plus Congestion Ultratabs, Medicine with Diphenhydramine HCl Antihistamine & Phenylephrine HCl Nasal Decongestant, Allergy & Sinus Congestion Relief Tablets, 24 ctBenadryl
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Breathe-X - Allergy & Sinus Relief Supplement - Supports Sinuses & Nasal Discomfort - Non-Drowsy & Fast-Acting - Quercetin, Bromelain, Citrus Bioflavonoids, Nettle Leaf & Vitamin C - 90 CapsulesLifeSeasons
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Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mLAfrin
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Bionorica Sinupret Kids Sinus & Immune Syrup Respiratory & Immunity Boost Natural, Fast Acting Herbal Support with Verbena & Elder Flower - Cherry Flavor - 3.38 ozBionorica
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Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)Afrin
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GenCare - Multi Symptom Non Drowsy Daytime Cold & Flu Relief Acetaminophen 325mg, Dextromethorphan HBr 10mg, Phenylephrine HCl 5mg (48 Softgels) Non Habit Forming Pain Reliever & Nasal DecongestantGenCare
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Vicks DayQuil Cold & Flu Medicine, Non-Drowsy Powerful Multi-Symptom Daytime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Nasal Congestion, Sinus Pressure and Cough, 48 LiquicapsVicks
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15% OffHealthA2Z Cold & Allergy Relief, Chlorpheniramine Maleate & Phenylephrine HCL, Dye Free, 24 Tablets x 3pack (72 Tablets)HealthA2Z
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14% OffSimply Saline Extra Strength for Severe Congestion Relief Nasal Mist: 4.6oz 3-PackArm & Hammer
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Berkley Jensen No Drip Severe Congestion Nasal Spray - Maximum Strength Decongestant with Oxymetazoline HCl & Menthol - Pump Mist Applicator, No Steroid, 12 Hour Relief, 1 Fl Oz (Pack of 3)berkley jensen
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Coricidin HBP Tablets Cold & Flu 40ctCoricidin HBP
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Genexa Flu Fix | Multi-Symptom Flu Remedy for Kids & Adults | Relieves Aches, Fever, Congestion | Acai Berry Flavor | Organic & Non-GMO | Homeopathic Remedy Made Clean | 60 Chewable Tablets, Ages 4+Genexa
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Vicks Sinex Saline Nasal Spray, Drug Free Ultra Fine Mist, Clear Everyday Sinus Congestion Fast, Clear Mucus from a Cold or Allergy, Daily Use 5.0 fl ozVicks
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Vicks Sinus Inhaler, Plug-in Non-Medicated Steam Inhaler for Sinus Relief, Allergies, Congestion & Colds, Vocal Steamer, Soothes Nasal & Throat Passages, Works with VapoPads (1 Included)Vicks
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SinuCleanse Vapor Inhaler, Made in USA, Portable, On-The-Go, Non-Medicated, Refreshing Vapors, Pack of 3 Vapor SticksSinuCleanse
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Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg, Antihistamine Tablets for Symptoms Due to Hay Fever and Upper Respiratory Allergies, Mini-Tabs, 100 CountAmazon Basic Care
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24% OffBoiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 DosesBoiron
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41% OffNeosynephrine, Nasal Spray for Cold Sinus Relief Extra Strength, Clear, 0.5 Fl OzNEO-SYNEPHRINE
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Amazon Basic Care No Drip Nasal Spray, 12 Hour Maximum Strength Nasal Decongestant, Oxymetazoline HCl, Fast-Acting Sinus Pressure Relief, 1 fl oz (Pack of 1)Amazon Basic Care
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Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 10 Coated TabletsAdvil
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ARM & HAMMER Simply Saline Nasal Care Daily Mist 4.5oz – Instant Relief for Every Day Congestion – One 4.5oz BottleArm & Hammer
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Afrin Original Maximum Strength 12 Hour Nasal Congestion Relief Spray - 3 bottles, 1 FL OZ (30mL) each. Total 3 FL OZ (90 mL)Afrin
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Amazon Basic Care Daytime Severe Cold & Flu Relief Caplets, Multi-Symptom Relief for Headache, Fever, Sore Throat, Chest & Nasal Congestion, Vapor Ice, 24 CountAmazon Basic Care
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Vicks Dayquil & Nyquil Severe Honey Flavor Co-Pack, Cold & Flu Medicine, Relieves Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, And Cough, 2X12OzVicks
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Natural Factors Lung, Bronchial & Sinus Health - Respiratory Health Supplement - Supports Lung & Sinus Health - Supports Healthy Lung Tissue & Mucus Consistency - 90 Tablets (90 Servings)Natural Factors
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25% OffAmazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, 24-Hour Relief for Allergy, 300 Count (Packaging may vary)Amazon Basic Care
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Sinus Plumber Pepper Nasal Spray, Allergy and Sinus Relief, Congestion, Headaches, 1 fl ozSinus Plumber
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10% OffVICKS Sinex Saline Extra Strength Nasal Spray, 3X Concentrated* Drug Free Ultra Fine Mist, Instantly Clears Mucus, Ultra Concentrated to Clear Congestion Fast, Safe For Daily Use, 5 OZ x 2Vicks
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38% OffFamilyCare Nasal Relief Spray, Pump Mist, Anti-drip, Severe Congestion, (Oxymetazoline HCI) 12 Hours, 3 PackFamily Care
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Xynase® Nasal Spray with Xylitol (0.75 fl oz) - All Natural Saline Gentle Relief for Congestion, Allergies, and Sinus Pressure, Safe for All AgesXynase
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Major Cough and Cold HBP Tablets - Antihistamine and Cough Suppressant for People with High Blood Pressure - Dextromethorphan HBr, Chlorpheniramine Maleate - 16 Count (1 Pack)MAJOR
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Amazon Basic Care No Drip Severe 12 Hour Nasal Decongestant Pump Mist, Maximum Strength Plus Menthol, Allergy Relief, 1 fl oz (Pack of 1)Amazon Basic Care
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14% OffMucinex Sinus Saline Nasal Spray & Sinus Rinse, Drug-Free, Additive Free, Non-Drowsy Nasal Irrigation with 2-in-1 Jet + Mist Spray Nozzle for Cold & Allergy Season, 4.5ozMucinex
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Sudafed OM Sinus Severe No Drip Nasal Spray with Cooling Menthol, Maximum Strength Sinus Decongestant for Fast Congestion & Pressure Relief, Oxymetazoline HCl .05% Nose Spray, 1 fl. ozSudafed
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HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Relief (24 Daytime & 12 Nighttime Softgels) (Combo (36 Count Pack of 1))HealthA2Z
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17% OffMAOEVER Nasal Irrigation System – Sinus Rinse Machine with Dual Water Tank, Automatic Waste Collection & Adjustable Water Flow, Congestion & Sinus Care, Positive Pressure(301ml)MAOEVER
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16% OffZicam Extreme Congestion Relief No-Drip Nasal Spray with Soothing Aloe Vera, 0.5 ozZicam
110 Sinus Medicine deals are available from:
Amazon, eBay stores, starting from $4.19.
The biggest discount we found is 50% on HealthA2Z® Decongestant PE | Phenylephrine HCl 10 mg | Nasal & Sinus Congestion Relief Due to Cold & Allergies (300 Count (Pack of 1)) at Amazon.
The lowest price we found is $4.19 while the highest is $49.99.
Prices for the best Sinus Medicine deals average at $14.94.
Last updated on July 5, 2026.
We scanned these quality online stores and more to deliver you with the best offers online available for Sinus Medicine.